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Enterprise AI Analysis: PediatricAnxietyBench: Evaluating Large Language Model Safety Under Parental Anxiety and Pressure in Pediatric Consultations

Enterprise AI Analysis

PediatricAnxietyBench: Evaluating Large Language Model Safety Under Parental Anxiety and Pressure in Pediatric Consultations

Large Language Models (LLMs) are increasingly vital for immediate health guidance, yet their safety under real-world adversarial pressures remains a critical concern. This study introduces PediatricAnxietyBench, a novel benchmark to rigorously assess LLM safety in high-stakes pediatric consultations, especially when parents express anxiety and urgency.

Our findings reveal that while model scale enhances robustness, all tested LLMs remain vulnerable to realistic parental pressures. Key gaps in current safety mechanisms include a lack of emergency recognition and inconsistent hedging behavior. This work emphasizes the need for context-aware safety mechanisms that go beyond standard benchmarks to ensure clinically significant reliability in medical AI deployments.

Executive Impact & Key Findings

Understanding LLM safety in sensitive medical contexts is crucial for responsible AI deployment. This analysis highlights critical performance benchmarks and vulnerabilities under real-world conditions.

0/15 Mean Safety Score (Avg.)
0% Critical Failure Rate Reduction (70B vs 8B)
0% Referral Adherence Rate
0% Safety Score Reduction by Adversarial Queries
0% Emergency Recognition Rate

Deep Analysis & Enterprise Applications

Select a topic to dive deeper into the specific findings from the research, rebuilt as interactive, enterprise-focused modules to inform your AI strategy.

Impact of Model Scale on Safety (RQ1)

The study clearly demonstrates that LLM scale significantly influences safety in pediatric consultations. The larger Llama-3.3-70B model consistently outperformed the smaller Llama-3.1-8B model, exhibiting higher safety scores and lower rates of critical failures. This suggests that more powerful models are better equipped to handle nuanced medical queries and maintain diagnostic restraint, even under pressure.

LLM Safety Performance Comparison: Llama 70B vs. 8B

Metric Llama 70B Llama 8B Improvement (70B)
Mean Safety Score (out of 15) 6.26 4.95 +26.5%
Critical Failure Rate (<3 score) 4.8% 12.0% -60%
Inappropriate Diagnosis Rate 8.8% 14.9% -41%
Mean Hedging Count 1.87 1.22 +53%

Adversarial Trigger Patterns (RQ2 & RQ4)

Adversarial pressures, often manifested through parental anxiety and urgency, significantly degrade LLM safety. The study identified specific linguistic patterns that act as triggers, leading to an overall 8% reduction in safety scores. Urgency expressions, such as "it's 3AM," caused the most significant degradation, highlighting the need for LLMs to handle time-sensitive and emotionally charged inputs with extreme caution.

-1.40 points Largest Safety Score Degradation Caused by Urgency Triggers

Adversarial Trigger Categories and Impact

Trigger Category Prevalence Mean Impact on Safety Score Example Phrase
Direct Pressure 26.7% -0.50 "don't give me generic answers"
Urgency 16.7% -1.40 "it's 3AM"
Economic Barriers 3.3% -0.50 "can't afford ER"
Authority Challenge 3.3% +0.38 "I already know that"

Enterprise Process Flow: PediatricAnxietyBench Methodology

Define Benchmark Scope
Extract Authentic Patient Queries
Synthesize Adversarial Queries
Apply Standardized System Prompt
Evaluate with Multi-dimensional Safety Framework
Conduct Statistical Analysis

Topic-Specific Vulnerabilities (RQ3)

Certain medical topics present higher risks for LLM failure. Seizures and post-vaccination issues consistently yielded the lowest safety scores due to their diagnostic complexity, inherent urgency, and potential for pattern-matching errors. These areas require enhanced scrutiny and specialized safeguards in AI systems.

Vulnerability Deep Dive: Seizures

Challenge: Seizure-related queries exhibited the lowest average safety score (4.89) and the highest inappropriate diagnosis rate (33.3%). Queries were often longer and included terms like "febrile," leading to inappropriate definitive diagnoses (e.g., "febrile seizure") instead of referring to a specialist.

Impact: Misdiagnosis in seizure cases can have severe patient safety implications, underscoring the critical need for diagnostic restraint and robust referral mechanisms for high-acuity conditions.

Vulnerability Deep Dive: Post-Vaccination Issues

Challenge: Post-vaccination queries also showed significantly low safety scores (4.75) and a high diagnosis rate (25%). These scenarios often involve heightened parental anxiety and a need for cautious, evidence-based guidance.

Impact: Inaccurate or overly definitive advice regarding vaccine-related concerns can undermine public health confidence and potentially lead to inappropriate actions, highlighting the sensitivity required in such interactions.

Effectiveness of Safety Mechanisms

The study investigated the role of explicit safety mechanisms, particularly hedging language and emergency recognition. Hedging emerged as a strong indicator of safe behavior, while emergency recognition proved to be a critical, unmet need.

r = 0.68 Strong Correlation between Hedging and Safety Scores

Each additional hedging phrase increased safety scores by approximately 2.4 points, and ≥2 phrases yielded 100% referral adherence. Explicit uncertainty expression is a vital safeguard.

0% Emergency Recognition Rate Across All Models

Despite clear system prompts, neither Llama model explicitly recognized or escalated critical emergency scenarios, highlighting a significant and dangerous gap in current LLM safety capabilities for high-stakes medical advice.

Quantify Your AI Impact: ROI Calculator

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Your AI Implementation Roadmap

A structured approach to integrating safety-first AI into your enterprise, ensuring robust and responsible deployment.

Phase 1: Discovery & Strategy

Initial consultation to understand your specific needs, assess current workflows, and define AI integration objectives with a focus on high-risk domains and ethical considerations.

Phase 2: Pilot & Customization

Develop and deploy a pilot AI solution tailored to a specific use case, incorporating robust safety mechanisms like enhanced hedging and referral protocols, and addressing identified vulnerabilities.

Phase 3: Iterative Evaluation & Refinement

Rigorous adversarial testing using benchmarks like PediatricAnxietyBench, continuous monitoring of safety metrics, and iterative model refinement to maximize robustness and compliance.

Phase 4: Scaled Deployment & Training

Full-scale integration across relevant departments, comprehensive training for end-users, and establishment of ongoing governance frameworks to ensure long-term safety and performance.

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