COMMUNICATIONS MEDICINE
Increasing engagement with cognitive-behavioral therapy (CBT) using generative Al: a randomized controlled trial (RCT)
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Executive Impact: Key Findings at a Glance
This RCT demonstrated that genAI-enabled therapy support has a significant and beneficial effect on increasing engagement with therapeutic exercises and materials. While the stand-alone genAI tool did not improve overall clinical outcomes compared to digital workbooks over six weeks, engagement with features providing clinical personalization was associated with stronger anxiety symptom reduction and enhanced overall wellbeing. Crucially, the use of this tool was safe when benchmarked against an active control.
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Engagement Frequency Increase
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Engagement Duration Increase
Comparable
Safety Profile
Improved
Personalization Impact
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